Using origami DNA to trap large viruses

A team of researchers from the Technical University of Munich and the University of Regensburg, both in Germany, has found that it is possible to build origami DNA structures that can be used to trap large viruses. In their paper published in the journal Cell Reports Physical Science, the group describes how they built their structures and how well they worked when tested.

DNA Origami News, Articles

Programming Dynamic Assembly of Viral Proteins with DNA Origami

Orientation-locked DNA origami for stable trapping of small proteins in the NEOtrap

DNA Origami News, Articles

Viral trapping by DNA origami shells – DNA-Robotics

Nano traps' to lock up and neutralize viruses •

When the Immune Response Makes COVID-19 Worse

DNA Origami: From Molecular Folding Art to Drug Delivery Technology - Jiang - Advanced Materials - Wiley Online Library

Versatile computer-aided design of free-form DNA nanostructures and assemblies

Reverse engineering DNA origami nanostructure designs from raw scaffold and staple sequence lists - Computational and Structural Biotechnology Journal

IgG mediated stabilization and antigen triggered disassembly of

Orientation-locked DNA origami for stable trapping of small proteins in the NEOtrap

Origami DNA Traps Could Keep Large Viruses From Infecting Cells: by engineering structures out of DNA, scientists could potentially prevent larger viruses, like coronaviruses and influenza viruses, from interacting with cells.

Organizing DNA Origami Tiles into Larger Structures Using Preformed Scaffold Frames