The Classical Complement Cascade Mediates CNS Synapse Elimination
Por um escritor misterioso
Last updated 01 julho 2024
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Cells, Free Full-Text
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PDF] Insight into the role of phosphatidylserine in complement-mediated synapse loss in Alzheimer's disease
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PDF) The Classical Complement Cascade Mediates CNS Synapse Elimination
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Microglia and complement mediate early corticostriatal synapse loss and cognitive dysfunction in Huntington's disease
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Classical complement cascade initiating C1q protein within neurons in the aged rhesus macaque dorsolateral prefrontal cortex, Journal of Neuroinflammation
![The Classical Complement Cascade Mediates CNS Synapse Elimination](https://www.researchgate.net/publication/361799234/figure/fig5/AS:1175033233850369@1657161162546/Proposed-role-of-membrane-attack-complex-MAC-in-complement-mediated-synapse-loss-a-In_Q320.jpg)
PDF) Terminal complement pathway activation drives synaptic loss in Alzheimer's disease models
![The Classical Complement Cascade Mediates CNS Synapse Elimination](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41582-020-0400-0/MediaObjects/41582_2020_400_Fig1_HTML.png)
Complement in neurological disorders and emerging complement-targeted therapeutics
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Frontiers Modulation of the Complement System by Neoplastic Disease of the Central Nervous System
![The Classical Complement Cascade Mediates CNS Synapse Elimination](https://www.biorxiv.org/content/biorxiv/early/2019/11/15/841601/F5.large.jpg)
Targeted complement inhibition at synapses prevents microglial synaptic engulfment and synapse loss in demyelinating disease
![The Classical Complement Cascade Mediates CNS Synapse Elimination](https://www.researchgate.net/publication/355932855/figure/fig1/AS:11431281090805033@1666190820125/Complement-mediated-synapse-elimination-begins-with-synaptic-C1q-deposition-followed-by.png)
Complement-mediated synapse elimination begins with synaptic C1q
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Full article: The case for complement component 5 as a target in neurodegenerative disease
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A new age for (mucosal) NeuroImmunology - Mucosal Immunology
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Microglial trogocytosis and the complement system regulate axonal pruning in vivo
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As a Potential Therapeutic Target, C1q Induces Synapse Loss Via Inflammasome-activating Apoptotic and Mitochondria Impairment Mechanisms in Alzheimer's Disease
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